What Glutathione is
Glutathione (GSH) is the tripeptide γ-L-glutamyl-L-cysteinylglycine. Unlike an ordinary peptide, its first bond is made through the side-chain (γ) carboxyl of glutamate rather than the backbone carboxyl, which protects it from most peptidases. Its cysteine thiol is the reactive centre: two glutathione molecules can be oxidized to the disulfide GSSG, and the GSH/GSSG pair is the main thiol redox buffer inside cells, which is why glutathione is one of the most widely used reagents in biochemistry and cell biology.
Glutathione Labs supplies reduced glutathione as a lyophilized powder in 600 mg vials. Every lot is tested by an independent laboratory for HPLC-UV purity, LC-MS identity and net content, with the certificate published here before sale through Klow.bio.
Structure
The free thiol makes glutathione sensitive to air oxidation, especially in solution, where it slowly converts to the disulfide GSSG (612.6 g/mol). LC-MS distinguishes the two easily. Keeping the powder sealed and dry limits that conversion.
complete Glutathione specifications.
Storage and handling
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. Lyophilized material absorbs moisture from the air, and absorbed moisture restarts the reactions that drying slows, so keep vials sealed until needed. Storage and stability guide.